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Start Over Collection Tags Research Data Sets Type Dataset Year Published 2021

1. Code and data from "Comparative genomic analysis reveals varying levels of mammalian adaptation to coronavirus infections"

Author(s):
King, Sean
Abstract:
Severe acute respiratory coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is of zoonotic origin. Evolutionary analyses assessing whether coronaviruses similar to SARS-CoV-2 infected ancestral species of modern-day animal hosts could be useful in identifying additional reservoirs of potentially dangerous coronaviruses. We reasoned that if a clade of species has been repeatedly exposed to a virus, then their proteins relevant for viral entry may exhibit adaptations that affect host susceptibility or response. We perform comparative analyses across the mammalian phylogeny of angiotensin-converting enzyme 2 (ACE2), the cellular receptor for SARS-CoV-2, in order to uncover evidence for selection acting at its binding interface with the SARS-CoV-2 spike protein. We uncover that in rodents there is evidence for adaptive amino acid substitutions at positions comprising the ACE2-spike interaction interface, whereas the variation within ACE2 proteins in primates and some other mammalian clades is not consistent with evolutionary adaptations. We also analyze aminopeptidase N (APN), the receptor for the human coronavirus 229E, a virus that causes the common cold, and find evidence for adaptation in primates. Altogether, our results suggest that the rodent and primate lineages may have had ancient exposures to viruses similar to SARS-CoV-2 and HCoV-229E, respectively. Included in this repository are the instructions and corresponding code required to build the dataset and run the analysis in the manuscript.
Type:
Dataset
Issue Date:
28 September 2021

2. CrvA and CrvB form a curvature-inducing module sufficient to induce cell shape complexity in Gram-negative bacteria

Author(s):
Martin, Nicholas R; Blackman, Edith; Bratton, Benjamin P; Chase, Katelyn J; Bartlett, Thomas M; Gitai, Zemer
Abstract:
Bacterial species have diverse cell shapes that enable motility, colonization, and virulence. The cell wall defines bacterial shape and is primarily built by two cytoskeleton-guided synthesis machines, the elongasome and the divisome. However, the mechanisms producing complex shapes, like the curved-rod shape of Vibrio cholerae, are incompletely defined. Previous studies have reported that species-specific regulation of cytoskeleton-guided machines enables formation of complex bacterial shapes such as cell curvature and cellular appendages. In contrast, we report that CrvA and CrvB are sufficient to induce complex cell shape autonomously of the cytoskeleton in V. cholerae. The autonomy of the CrvAB module also enables it to induce curvature in the Gram-negative species Escherichia coli, Pseudomonas aeruginosa, Caulobacter crescentus, and Agrobacterium tumefaciens. Using inducible gene expression, quantitative microscopy, and biochemistry we show that CrvA and CrvB circumvent the need for patterning via cytoskeletal elements by regulating each other to form an asymmetrically-localized, periplasmic structure that directly binds to the cell wall. The assembly and disassembly of this periplasmic structure enables dynamic changes in cell shape. Bioinformatics indicate that CrvA and CrvB may have diverged from a single ancestral hybrid protein. Using fusion experiments in V. cholerae, we find that a synthetic CrvA/B hybrid protein is sufficient to induce curvature on its own, but that expression of two distinct proteins, CrvA and CrvB, promotes more rapid curvature induction. We conclude that morphological complexity can arise independently of cell shape specification by the core cytoskeleton-guided synthesis machines.
Type:
Dataset
Issue Date:
2021

3. Data corresponding to our paper on "Chemotactic smoothing of collective migration"

Author(s):
Bhattacharjee, Tapomoy; Amchin, Daniel; Alert, Ricard; Ott, Jenna; Datta, Sujit
Abstract:
Collective migration -- the directed, coordinated motion of many self-propelled agents -- is a fascinating emergent behavior exhibited by active matter that has key functional implications for biological systems. Extensive studies have elucidated the different ways in which this phenomenon may arise. Nevertheless, how collective migration can persist when a population is confronted with perturbations, which inevitably arise in complex settings, is poorly understood. Here, by combining experiments and simulations, we describe a mechanism by which collectively migrating populations smooth out large-scale perturbations in their overall morphology, enabling their constituents to continue to migrate together. We focus on the canonical example of chemotactic migration of Escherichia coli, in which fronts of cells move via directed motion, or chemotaxis, in response to a self-generated nutrient gradient. We identify two distinct modes in which chemotaxis influences the morphology of the population: cells in different locations along a front migrate at different velocities due to spatial variations in (i) the local nutrient gradient and in (ii) the ability of cells to sense and respond to the local nutrient gradient. While the first mode is destabilizing, the second mode is stabilizing and dominates, ultimately driving smoothing of the overall population and enabling continued collective migration. This process is autonomous, arising without any external intervention; instead, it is a population-scale consequence of the manner in which individual cells transduce external signals. Our findings thus provide insights to predict, and potentially control, the collective migration and morphology of cell populations and diverse other forms of active matter.
Type:
Dataset
Issue Date:
24 June 2021

5. Data for: 'Facies control on carbonate δ13C on the Great Bahama Bank'

Author(s):
Geyman, Emily C.; Maloof, Adam C.
Abstract:
The carbon isotopic (δ13C) composition of shallow-water carbonates often is interpreted to reflect the δ13C of the global ocean and is used as a proxy for changes in the global carbon cycle. However, local platform processes, in addition to meteoric and marine diagenesis, may decouple carbonate δ13C from that of the global ocean. To shed light on the extent to which changing sediment grain composition may produce δ13C shifts in the stratigraphic record, we present new δ13C measurements of benthic foraminifera, solitary corals, calcifying green algae, ooids, coated grains, and lime mud from the modern Great Bahama Bank (GBB). This survey of a modern carbonate environment reveals δ13C variability comparable to the largest δ13C excursions in the last two billion years of Earth history.
Type:
Dataset
Issue Date:
6 May 2021

6. Data for: 'How is sea level change encoded in carbonate stratigraphy?'

Author(s):
Geyman, Emily C.; Maloof, Adam C.; Dyer, Blake
Abstract:
The history of organismal evolution, seawater chemistry, and paleoclimate is recorded in layers of carbonate sedimentary rock. Meter-scale cyclic stacking patterns in these carbonates often are interpreted as representing sea level change. A reliable sedimentary proxy for eustasy would be profoundly useful for reconstructing paleoclimate, since sea level responds to changes in temperature and ice volume. However, the translation from water depth to carbonate layering has proven difficult, with recent surveys of modern shallow water platforms revealing little correlation between carbonate facies (i.e., grain size, sedimentary bed forms, ecology) and water depth. We train a convolutional neural network with satellite imagery and new field observations from a 3,000 km2 region northwest of Andros Island (Bahamas) to generate a facies map with 5 m resolution. Leveraging a newly-published bathymetry for the same region, we test the hypothesis that one can extract a signal of water depth change, not simply from individual facies, but from sequences of facies transitions analogous to vertically stacked carbonate strata. Our Hidden Markov Model (HMM) can distinguish relative sea level fall from random variability with ∼90% accuracy. Finally, since shallowing-upward patterns can result from local (autogenic) processes in addition to forced mechanisms such as eustasy, we search for statistical tools to diagnose the presence or absence of external forcings on relative sea level. With a new data-driven forward model that simulates how modern facies mosaics evolve to stack strata, we show how different sea level forcings generate characteristic patterns of cycle thicknesses in shallow carbonates, providing a new tool for quantitative reconstruction of ancient sea level conditions from the geologic record.
Type:
Dataset
Issue Date:
1 February 2021

7. Data from "Vapor-liquid equilibrium of water with the MB-pol many-body potential"

Author(s):
Muniz, Maria Carolina; Gartner III, Thomas E.; Riera, Marc; Knight, Christopher; Yue, Shuwen; Paesani, Francesco; Panagiotopoulos, Athanassios Z.
Abstract:
This dataset contains all data (including input files, simulation trajectories as well as other data files and analysis scripts) related to the publication "Vapor-liquid equilibrium of water with the MB-pol many-body potential" by Muniz et al. in preparation (2021). In this work, we assessed the performance of the MB-pol many-body potential with respect to water's vapor-liquid equilibrium properties. Through the use of direct coexistence molecular dynamics, we calculated properties such as coexistence densities, surface tension, vapor pressures and enthalpy of vaporization. We found that MB-pol is able to predict these properties in good agreement with experimental data. The results attest to the chemical accuracy of MB-pol and its large range of application across water's phase diagram.
Type:
Dataset
Issue Date:
2021

9. Delivery Gig Worker Interviews on Automation at Work

Author(s):
Enriquez, Diana
Abstract:
These data include 39 structured interview transcripts. Each case is someone who worked at the time for Uber, UberEats, Lyft, and/or Amazon Flex (Amazon’s contractor delivery service). These data were collected between July and September 2019. All but one of the interviews occurred over the phone. My questions are focused on the structure of their gig work jobs and the technology they used at work or expected to use at work in the future. I included a description of the data, the recruitment methods, and the discussion guide in this ReadMe file. 
Type:
Dataset
Issue Date:
21 September 2021

10. Derrida's Margins datasets

Author(s):
Chenoweth, Katie; Koeser, Rebecca Sutton; Altergott, Renée; Baron-Raiffe, Alexander; Bauer, Jean; Budak, Nick; Córdova, Chad; Hancock, Austin; Hicks, Benjamin; McElwee, Kevin; Vettier, Chloé
Abstract:
Derrida’s Margins <derridas-margins.princeton.edu> is a website and online research tool for annotations from the Library of Jacques Derrida, housed at Princeton University Library (PUL) <library.princeton.edu>. Jacques Derrida is one of the major figures of twentieth-century thought, and his library--which bears the traces of decades of close reading--represents a major intellectual archive. This project focused on annotations related to Derrida’s landmark 1967 work De la grammatologie (Of Grammatology).
Type:
Dataset
Issue Date:
29 October 2021

11. Derrida's Margins datasets

Author(s):
Chenoweth, Katie; Baron-Raiffe, Alexander; Sutton Koeser, Rebecca
Abstract:
Derrida’s Margins <derridas-margins.princeton.edu> is a website and online research tool for annotations from the Library of Jacques Derrida, housed at Princeton University Library (PUL) <library.princeton.edu>. Jacques Derrida is one of the major figures of twentieth-century thought, and his library--which bears the traces of decades of close reading--represents a major intellectual archive. This project focused on annotations related to Derrida’s landmark 1967 work De la grammatologie (Of Grammatology).
Type:
Dataset
Issue Date:
15 October 2021

12. Estimated The New York Times paragraph- and article-level sentiment on China topics, and aggregated survey attitude toward China

Author(s):
Huang, Junming; Cook, Gavin; Xie, Yu
Abstract:
Here we publish the data used in paper "Junming Huang, Gavin Cook, and Yu Xie, Large-scale Quantitative Evidence of Media Impact on Public Opinion toward China". This dataset include estimated sentiments on The New York Times on China in eight topics from 1970 to 2019, and a time series of public attitude aggregated from surveys on China.
Type:
Dataset
Issue Date:
July 2021

13. Experimental data for paper "hydraulic transmissivity inferred from ice-sheet relaxation following Greenland supraglacial lake drainages"

Author(s):
Lai, Ching-Yao
Abstract:
This setup mimics ice lying above the drainage system. In the experiment, a fluid-filled blister is generated via liquid injection into the interface between a transparent elastic layer and a porous substrate. After injection of liquid, the fluid permeates from the blister through the porous substrate, the blister volume V(t) relaxes exponentially with time. Our lab experiments show that varying the permeability of the porous substrate k significantly impacts the relaxation timescale in the experiments.
Type:
Dataset
Issue Date:
18 May 2021

14. Integrative Mechanisms of Social Attention

Author(s):
Bio, Branden; Graziano, Michael
Abstract:
Monitoring the attention of others is fundamental to social cognition. Most of the literature on the topic assumes that our social cognitive machinery is tuned specifically to the gaze direction of others as a proxy for attention. This standard assumption reduces attention to an externally visible parameter. Here we show that this assumption is wrong and a deeper, more meaningful representation is involved. We presented subjects with two cues about the attentional state of a face: direction of gaze and emotional expression. We tested whether people relied predominantly on one cue, the other, or both. If the traditional view is correct, then the gaze cue should dominate. Instead, people employed a variety of strategies, some relying on gaze, some on expression, and some on an integration of cues. We also assessed people’s social cognitive ability using two, independent, standard tests. If the traditional view is correct, then social cognitive ability, as assessed by the independent tests, should correlate with the degree to which people successfully use the gaze cue to judge the attention state of the face. Instead, social cognitive ability correlated best with the degree to which people successfully integrated the cues together, instead of with the use of any one specific cue. The results suggest a rethink of a fundamental component of social cognition: monitoring the attention of others involves constructing a deep model that is informed by a combination of cues. Attention is a rich process and monitoring the attention of others involves a similarly rich representation.
Type:
Dataset
Issue Date:
22 July 2021

16. Shakespeare and Company Project Dataset: Lending Library Books

Author(s):
Kotin, Joshua; Koeser, Rebecca Sutton; Adair, Carl; Alagappan, Serena; Allen, Paige; Bauer, Jean; Browne, Oliver J.; Budak, Nick; Calver, Harriet; Chow, Jin Yun; Davis, Ian; Doroudian, Gissoo; Engel, Currie; Gautreau, Violet; Gjaja, Alex; Green, Elspeth; Hart, Isaac; Hicks, Benjamin; Joelson, Madeleine E.; Kelly, Carolyn; Krolewski, Sara; Li, Xinyi; Maag, Ellie; Macksey, Elizabeth; Mahoney, Cate; Mancino, Francesca; McCarthy, Jesse D.; Naydan, Mary; Root, Sally; Ruehl, Isabel; Thode, Sylvie; Vandermel, Katherine; VanSant, Camey; Wulfman, Clifford E.
Abstract:
This dataset includes information about approximately 6,000 books and other items with bibliographic data as well as summary information about when the item circulated in the Shakespeare and Company lending library and the number of times an item was borrowed or purchased.
Type:
Dataset
Issue Date:
29 January 2021

17. Shakespeare and Company Project Dataset: Lending Library Events

Author(s):
Kotin, Joshua; Koeser, Rebecca Sutton; Adair, Carl; Alagappan, Serena; Allen, Paige; Bauer, Jean; Browne, Oliver J.; Budak, Nick; Calver, Harriet; Chow, Jin Yun; Davis, Ian; Doroudian, Gissoo; Engel, Currie; Gautreau, Violet; Gjaja, Alex; Green, Elspeth; Hart, Isaac; Hicks, Benjamin; Joelson, Madeleine E.; Kelly, Carolyn; Krolewski, Sara; Li, Xinyi; Maag, Ellie; Macksey, Elizabeth; Mahoney, Cate; Mancino, Francesca; McCarthy, Jesse D.; Naydan, Mary; Root, Sally; Ruehl, Isabel; Thode, Sylvie; Vandermel, Katherine; VanSant, Camey; Wulfman, Clifford E.
Abstract:
The Shakespeare and Company Project: Lending Library Events dataset includes information about approximately 35,000 lending library events including membership activities such as subscriptions, renewals and reimbursements and book-related activities such as borrowing and purchasing. For events related to lending library cards that are available as digital surrogates, IIIF links are provided.
Type:
Dataset
Issue Date:
29 January 2021

18. Shakespeare and Company Project Dataset: Lending Library Members

Author(s):
Kotin, Joshua; Koeser, Rebecca Sutton; Adair, Carl; Alagappan, Serena; Allen, Paige; Bauer, Jean; Browne, Oliver J.; Budak, Nick; Calver, Harriet; Chow, Jin Yun; Davis, Ian; Doroudian, Gissoo; Engel, Currie; Gautreau, Violet; Gjaja, Alex; Green, Elspeth; Hart, Isaac; Hicks, Benjamin; Joelson, Madeleine E.; Kelly, Carolyn; Krolewski, Sara; Li, Xinyi; Maag, Ellie; Macksey, Elizabeth; Mahoney, Cate; Mancino, Francesca; McCarthy, Jesse D.; Naydan, Mary; Root, Sally; Ruehl, Isabel; Thode, Sylvie; Vandermel, Katherine; VanSant, Camey; Wulfman, Clifford E.
Abstract:
The Shakespeare and Company Project: Lending Library Members dataset includes information about approximately 5,600 members of Sylvia Beach's Shakespeare and Company lending library.
Type:
Dataset
Issue Date:
29 January 2021

19. Shakespeare and Company Project Dataset: Lending Library Members, Books, Events

Author(s):
Kotin, Joshua; Koeser, Rebecca Sutton; Adair, Carl; Alagappan, Serena; Allen, Paige; Bauer, Jean; Browne, Oliver J.; Budak, Nick; Calver, Harriet; Chow, Jin Yun; Davis, Ian; Doroudian, Gissoo; Engel, Currie; Gautreau, Violet; Gjaja, Alex; Green, Elspeth; Hart, Isaac; Hicks, Benjamin; Joelson, Madeleine E.; Kelly, Carolyn; Krolewski, Sara; Li, Xinyi; Maag, Ellie; Macksey, Elizabeth; Mahoney, Cate; Mancino, Francesca; McCarthy, Jesse D.; Naydan, Mary; Root, Sally; Ruehl, Isabel; Thode, Sylvie; Vandermel, Katherine; VanSant, Camey; Wulfman, Clifford E.
Abstract:
The Shakespeare and Company Project makes three datasets available to download in CSV and JSON formats. The datasets provide information about lending library members; the books that circulated in the lending library; and lending library events, including borrows, purchases, memberships, and renewals. The datasets may be used individually or in combination site URLs are consistent identifiers across all three. The DOIs for each dataset are as follows: Members (https://doi.org/10.34770/nsa4-3t76); Books (https://doi.org/10.34770/079z-h206); Events (https://doi.org/10.34770/rtbp-kv40).
Type:
Dataset
Issue Date:
29 January 2021

20. The 21st year: transcription, motif list, and relation score

Author(s):
Chang, Claire H. C.; Lazaridi, Christina; Yeshurun, Yaara; Norman, Kenneth A.; Hasson, Uri
Abstract:
This study examined how the brain dynamically updates event representations by integrating new information over multiple minutes while segregating irrelevant input. A professional writer custom-designed a narrative with two independent storylines, interleaving across minute-long segments (ABAB). In the last (C) part, characters from the two storylines meet and their shared history is revealed. Part C is designed to induce the spontaneous recall of past events, upon the recurrence of narrative motifs from A/B, and to shed new light on them. Our fMRI results showed storyline-specific neural patterns, which were reinstated (i.e. became more active) during storyline transitions. This effect increased along the processing timescale hierarchy, peaking in the default mode network. Similarly, the neural reinstatement of motifs was found during part C. Furthermore, participants showing stronger motif reinstatement performed better in integrating A/B and C events, demonstrating the role of memory reactivation in information integration over intervening irrelevant events.
Type:
Dataset and text
Issue Date:
2021

21. The Dielectric Function of "Astrodust", and Absorption and Scattering Cross Sections for Spheroids

Author(s):
Draine, Bruce T.; Hensley, Brandon S.
Abstract:
The dielectric function for "Astrodust" grain material is provided for different assumed values of the dust grain shape (spheroid axis ratio) and porosity (vacuum fraction), and fraction of the interstellar iron present as metallic inclusions. For each case, the dielectric function is obtained by requiring that the grains reproduce the observed infrared opacity, and match to a physically reasonable dielectric function at 1 micron, and extending to X-ray energies. The derived dielectric functions satisfy the Kramers-Kronig relations. Dielectric functions are provided from 1 Angstrom to 5 cm (12.4 keV to 2.59e-5 eV). For each dielectric function, we also calculate absorption and scattering corss sections for spheroidal grains, for three orientations of the grain relative to incident linearly-polarized light, for wavelengths from the Lyman limit (0.0912 micron) to the microwave (4 cm), and grain "effective radii" a_eff from 3.162A to 5.012 micron.
Type:
Dataset
Issue Date:
2021

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